FASENRA (benralizumab subcutaneous injection) Patient Assistance Program
Don’t let the high cost of brand anti-IL-5 receptor biologic disrupt your severe eosinophilic asthma care. We help eligible patients access Fasenra (benralizumab subcutaneous injection) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
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Key Takeaways:
- Fasenra (benralizumab) is FDA-approved as add-on maintenance treatment of severe eosinophilic asthma in patients ≥6 years old and for adults with eosinophilic granulomatosis with polyangiitis (EGPA). Anti-IL-5 receptor alpha (IL-5Rα) monoclonal antibody — depletes eosinophils via ADCC. Subcutaneous injection every 4 weeks for first 3 doses, then every 8 weeks.
- Without assistance, brand Fasenra costs commonly run approximately $5,000–$6,500 per dose (annualized $35,000–$50,000).
- Through AffordMyPrescriptions, qualifying patients can access Fasenra for a flat $69.95 per month.
- Other anti-eosinophilic asthma biologics: Nucala (mepolizumab — anti-IL-5 ligand), Cinqair (reslizumab — anti-IL-5 ligand, IV), Tezspire (tezepelumab — anti-TSLP, broader). Anti-IgE: Xolair (omalizumab — also for chronic rhinosinusitis with nasal polyps, urticaria). Anti-IL-4Rα: Dupixent (dupilumab — Type 2 inflammation broadly, including atopic derm, EoE, prurigo nodularis, CRSwNP). Standard maintenance: ICS-LABA combinations (Symbicort going generic, Advair/Wixela Inhub generic, Breo, Dulera) plus triple-therapy inhalers (Trelegy, Breztri) and biologics for severe disease.
What is Fasenra Prescription Assistance Program?
The Fasenra Patient Assistance Program is a manufacturer-sponsored initiative that helps eligible patients access Fasenra (used as add-on maintenance for severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis) at little or no cost when they meet specific income, insurance, and clinical criteria. The program is free to apply for, but the enrollment process involves detailed applications, specialty pulmonology/allergy/rheumatology coordination, blood eosinophil documentation, supporting documentation, and ongoing renewal — which can be overwhelming when you are already managing severe asthma exacerbations or vasculitis.
At AffordMyPrescriptions, our Patient Advocates handle the entire Fasenra PAP enrollment for a flat $69.95 per month. We complete the application, coordinate with your prescriber for required medical documentation (including eosinophil count and prior therapy history), follow up with the manufacturer’s program until approval, manage your every-4-week then every-8-week injections, and handle annual re-certification — so you never face a gap in your Fasenra biologic therapy.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your Fasenra enrollment — from the initial application through ongoing refills and annual re-enrollment — so you never face a gap in your severe asthma or EGPA treatment.
Pharmacy Price Comparison
- Without assistance, Fasenra costs thousands of dollars per dose at retail and specialty pharmacies. Discount cards and pharmacy coupons offer minimal relief at this price point, but a Patient Assistance Program can make this biologic accessible if you qualify. The table below compares typical retail pricing across major pharmacies to what you'd pay with our Fasenra advocacy service:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$6,300/dose | Save substantially |
| CVS Pharmacy | ~$6,500/dose | Save substantially |
| Walmart | ~$5,200/dose | Save substantially |
| Costco | ~$5,000/dose | Save substantially |
| Kroger | ~$3,800/dose | Alt anti-IL-5 biologic |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. AffordMyPrescriptions Advocacy Service bypasses pharmacy pricing entirely by using the manufacturer’s assistance program to secure your Fasenra — independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Fasenra Prescription Program?
The Fasenra Patient Assistance Program is free to apply and provides medication at no cost if approved. But the process involves detailed applications, prescriber coordination, documentation, and ongoing management — applications that are commonly delayed or denied when paperwork is incomplete. Our $69.95 per month covers full advocacy: applications, doctor coordination, documentation, refill management, and re-enrollment — so you focus on your health, not paperwork. Optimal asthma control requires good maintenance ICS-LABA therapy plus biologic add-on for severe eosinophilic phenotype.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Fasenra:
Limitations of Coupons
Prices fluctuate — savings aren’t guaranteed month-to-month
Copay accumulators may prevent savings from counting toward your deductible
- Coupon cards expire and require constant renewal
- Still $5,000–$6,500/dose per month even with the best discount
Cannot be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of injection cost
- No expiration — continuous access as long as you qualify
Medication supplied directly through the assistance program
We manage all paperwork, refills, and annual renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Fasenra assistance.
- You are a U.S. citizen or legal resident
- You Have A Valid Fasenra Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured, Underinsured, Or A Medicare Part D Beneficiary
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Understanding Fasenra:
Fasenra is a humanized monoclonal antibody targeting the alpha subunit of the IL-5 receptor on eosinophils. Unlike Nucala and Cinqair (which bind the IL-5 ligand), Fasenra induces antibody-dependent cellular cytotoxicity (ADCC) — directly depleting eosinophils. Convenient every-8-week dosing after initial loading. Targets severe eosinophilic asthma and EGPA.
How it works:
Eosinophils are key drivers of inflammation in severe eosinophilic asthma — releasing toxic granule proteins, leukotrienes, and cytokines that damage airway tissue and drive exacerbations. IL-5 promotes eosinophil maturation, activation, and survival.
Fasenra binds IL-5Rα on eosinophils and recruits NK cells via ADCC — depleting peripheral blood and tissue eosinophils nearly completely. Reduces severe asthma exacerbations, oral corticosteroid use, and improves lung function. Onset of benefit within 4 weeks; sustained with every-8-week maintenance after loading.
Form and use:
Fasenra 30 mg subcutaneous injection in upper arm, thigh, or abdomen. Loading: one injection every 4 weeks for first 3 doses. Maintenance: one injection every 8 weeks. Auto-injector pen and pre-filled syringe available. Refrigerate; allow to reach room temperature 30 min before injection.
Generic availability:
No biosimilar Fasenra. Other anti-eosinophilic biologics: Nucala (mepolizumab — anti-IL-5 ligand, monthly SC), Cinqair (reslizumab — anti-IL-5 ligand, weight-based IV monthly). Anti-IgE: Xolair (omalizumab) for severe allergic asthma, also CRSwNP, chronic spontaneous urticaria. Anti-IL-4Rα: Dupixent (dupilumab) — Type 2 inflammation broadly. Anti-TSLP: Tezspire (tezepelumab) — independent of eosinophil count, broader phenotypes. Standard inhaled maintenance: ICS-LABA (Symbicort going generic, Advair/Wixela generic, Breo, Dulera), triple therapy (Trelegy, Breztri), generic ICS (budesonide, fluticasone). Pulmonary rehabilitation, vaccinations, smoking cessation.
Warnings:
Hypersensitivity reactions (anaphylaxis, angioedema, urticaria — usually within hours to days), helminth infection (treat pre-existing helminth before starting), do not use to treat acute asthma exacerbations or status asthmaticus, oral corticosteroid taper should be gradual after Fasenra initiation, injection site reactions, headache, pharyngitis. Pregnancy: limited human data — IgG antibody crosses placenta. Lactation: limited data. Live vaccines: timing considerations.
FAQ (Frequently Asked Questions)
How Much Does Fasenra Cost Without Insurance?
$5,000–$6,500 per dose. Annualized cost $35,000–$50,000. Patient assistance programs and copay support are essential for most patients to access this therapy.
What is the difference between Fasenra and Nucala for severe asthma?
Both target the IL-5 pathway in eosinophilic asthma. Nucala (mepolizumab) binds the IL-5 ligand and is dosed monthly. Fasenra (benralizumab) binds the IL-5 receptor on eosinophils and recruits NK cells to deplete eosinophils — also offers every-8-week dosing after loading. Both reduce exacerbations and oral steroid use. Choice often by dosing preference, insurance coverage, and patient response history.
Why do tuberculosis and hepatitis B screening considerations apply to Fasenra?
While Fasenra does not carry the same formal screening requirements as TNF inhibitors, immunomodulatory biologics in patients with chronic infections require clinical judgment. Screen and treat pre-existing helminth infection before starting Fasenra. Discuss vaccination, TB and HBV history with your specialist.
How long does it take for Fasenra to start working?
Many patients notice reduced exacerbations and steroid burst frequency within the first 4–12 weeks. Lung function and symptom control continue improving over 6 months. Reassess response at 4–6 months — if inadequate, consider switching biologic class.
Can I stop my inhaled corticosteroid after starting Fasenra?
No — Fasenra is add-on therapy to standard maintenance ICS-LABA. Inhaled maintenance therapy should continue. Oral corticosteroid taper (for steroid-dependent severe asthma) is appropriate after Fasenra response and should be gradual, supervised by your specialist.
Can I get live vaccines while taking Fasenra?
Caution and timing considerations apply for live vaccines with any immunomodulator. Discuss with your specialist. Inactivated vaccines (annual flu, pneumococcal, COVID-19) are generally appropriate and recommended in severe asthma populations.
What happens if my Fasenra Patient Assistance Program application is denied?
We help explore Nucala or Tezspire copay programs (alternative biologics with similar mechanisms or broader phenotype coverage), Xolair for IgE-mediated allergic asthma, Dupixent for Type 2 inflammation, manufacturer copay programs, foundation aid (AAFA, Allergy and Asthma Network, COPD Foundation, EGPA-related vasculitis groups), and Medicare Part D/Part B coverage options for biologic injections.
Take Control of Your Medication Costs
Severe eosinophilic asthma and EGPA biologic therapy should not be derailed by cost. Our Fasenra advocacy team is ready to verify your eligibility, complete the manufacturer application on your behalf, and manage your prescription through approval, delivery, and renewal — for a flat $69.95 per month. If we cannot help you access Fasenra through a Patient Assistance Program, you are not charged. Call (833) 556-2729 or check your eligibility online today.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.